► Aviomarin (dimhenhydrinate) - Practical Medicine

Aviomarin (dimenhydrinate) - tablets

The name of the preparation Character; dose; package Manufacturer Price 100% Price after refund In which pharmacy?
Aviomarin tablets; 50 mg; 10 tables Teva Pharmaceuticals Polska 14.49 Check
Aviomarin tablets; 50 mg; 5 tables Teva Pharmaceuticals Polska 10.49 Check

Note: reimbursed drug prices are in line with the regulations in force from July 1, 2018.

The preparation contains the substance:dimenhydrinate

The drug is available without a prescription

What is Aviomarin?

The drug against nausea and vomiting.

What does Aviomarin contain and how does it work?

The active substance is dimenhydrinate (another name is dimenhydramine). It is an anti-emetic, antihistamine (reduces the effect of histamine) and cholinolytic (blocks muscarinic receptors for acetylcholine). Used anti-emetic and against nausea, especially in motion sickness. It penetrates the blood-brain barrier, has a strong inhibitory effect on the emetic center in the medulla and labyrinth reflexes. The antiemetic action is intensified by the cholinolytic properties. The product reduces the tone of smooth muscles, reduces gastrointestinal motility and reduces the secretion of saliva.
Dimenhydrin is well absorbed after oral administration. The onset of action occurs after about 30 minutes, the effect persists for 3-6 hours. Metabolized in the liver. Fully excreted through the kidneys within 24 hours after a single dose.

When to use Aviomarin?

The preparation is indicated:
· In the prevention of motion sickness
· In the prevention of nausea and vomiting and in their treatment (except for nausea and vomiting induced by drugs used in cancer chemotherapy).

When not to use this preparation?

Unfortunately, even if there are indications to use the preparation, it can not always be used. You can not use the product if you are allergic (you are hypersensitive) to any of the ingredients or other antihistamines.
Do not use if it occurs:
· Asthma attack
· Glaucoma with a closed angle of perception
· Pheochromocytoma
· porphyria
· Prostatic hyperplasia, residual urine in the bladder
· Epilepsy.
Do not use the preparation in children under 6 years of age.

Take special care with Aviomarin?

Certain diseases and other circumstances may constitute a contraindication to use or indication to change the dosage of the preparation. In some situations it may be necessary to carry out specific check-ups.
Caution should be exercised when using the preparation in:
· With liver problems
· With hyperthyroidism
· With reduced heart rate (bradycardia)
· With hypertension
· With a reduced level of potassium or magnesium in the blood (hypokalaemia or hypomagnesemia)
· With chronic respiratory disorders, with asthma
· With pyloric stenosis
· With congenital QT prolongation in ECG or other clinically significant cardiac dysfunction (eg ischemic heart disease, cardiovascular disease, cardiac arrhythmias)
· When you are taking medicines that cause QT prolongation on the ECG or drugs that reduce the amount of potassium in your blood (hypokalaemia).

Does this preparation affect the ability to drive vehicles?
The product significantly limits the psychomotor efficiency and significantly impairs the ability to drive vehicles and operate equipment / machines. Persons driving vehicles or operating machines / devices should not use the preparation.

Dosage of Aviomarin

The preparation is in the form of tablets for oral use.The tablets should be taken 30 minutes before traveling or taking a poorly tolerated medicine with water. Can be taken regardless of meals. Do not exceed the recommended doses because it will not increase the effectiveness of the drug and may harm your health and life. If you have any doubts regarding the use of the preparation, consult a physician.
Adults and adolescents after the age of 14: 50-100 mg, if necessary, can be repeated every 4-6 hours. Do not exceed the 400 mg dose a day.
Children 6-14. year of life: 50 mg, if necessary, it can be repeated every 6-8 hours. Do not exceed the dose of 5 mg / kg body weight per day and not more than 150 mg daily.
The product is intended for children who can swallow a tablet by themselves.
Due to the content of the active substance (50 mg) the preparation is not intended for children under 6 years of age.

Can I use Aviomarin during pregnancy and breastfeeding?

During pregnancy, do not use any medicine without consulting your doctor!
It is very important that before using any medicine during pregnancy or breastfeeding, consult a physician and explain beyond any doubt the potential risks and benefits associated with the use of the drug. If you are pregnant or planning to become pregnant, consult your doctor before using the product.
Do not use in the third trimester of pregnancy. The use of the preparation in the first or second trimester of pregnancy is allowed only if the doctor deems it absolutely necessary and if in the physician's opinion the expected benefits clearly outweigh the possible risks. Only a doctor can assess the benefit / risk ratio in your case!
The active substance in the preparation (dimenhydrinate) passes into breast milk. The preparation should not be used during breastfeeding unless the physician, considering the expected benefits and possible risks, considers use of the preparation as indicated. In this case, the doctor will also recommend appropriate precautions and necessary tests.

Can I use other preparations in parallel?

Tell your doctor about all medicines you have recently taken, including those that are over the counter.
Alcohol should not be consumed while using the product, as it may increase the effect of the preparation.
It must not be used in combination with central nervous system depressants (eg hypnotics, sedatives, barbiturates, muscle relaxants, narcotic analgesics); possible worsening of central nervous system depression.
The preparation may increase the effect of anticholinergic medicines (eg atropine, tricyclic antidepressants). The concurrent use of MAO inhibitors increases the cholinolytic activity of the preparation.
The preparation works synergistically with diazepam; has an antagonistic effect on amphetamine and its derivatives.
It weakens the effect of corticosteroids and oral anticoagulants.
The preparation used with bismuth salts and analgesics, psychotropic drugs and scopolamine may cause visual impairment.
Particular caution is advised when using the product with drugs that prolong the ECG QT interval (such as, for example, class IA or III antiarrhythmics, some antibiotics, eg erythromycin, antimalarials, antihistamines, neuroleptics) and with drugs that cause hypokalaemia (e.g. some diuretics).
The preparation used with antibiotics that exhibit ototoxic effects, i.e., damaging hearing (e.g., streptomycin, neomycin, vomycin, kanamycin, amikacin) can mask the symptoms of hearing loss by an antibiotic.
The use of the preparation should be discontinued for at least 3 days (as directed by the physician) before the planned allergy tests due to the possibility of obtaining false-negative results.

What side effects can occur?

Like all medicines, Aviomarin can cause side effects, although they will not occur in all patients who use this medicine. Remember that the expected benefits of using the drug are usually greater than the damage resulting from the occurrence of side effects.
Very common: drowsiness, dizziness, impaired concentration. Common: visual impairment, increased intraocular pressure, nausea, vomiting, constipation, diarrhea, abdominal pain, dry mouth, difficulty urinating, muscle weakness, fatigue, agitation, sleep disturbances, anxiety, tremor (paradoxical reactions are particularly in children). Rare: increased heart rate (tachycardia), hypotension, headache, insomnia, allergic skin reactions, skin hypersensitivity to light, liver dysfunction, cholestatic jaundice, hemolytic anemia. Very rare: exfoliative dermatitis, decreased appetite.