|The name of the preparation
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Note: reimbursed drug prices are in line with the regulations in force from July 1, 2018.
The preparation contains the substance:pantoprazole
The drug is available without a prescription
What is Anesteloc Max?
A drug that inhibits the secretion of hydrochloric acid in the stomach, containing a proton pump inhibitor.
What does Anesteloc Max contain and how does it work?
The active substance of the preparation is Pantoprazole
, a benzimidazole derivative, a drug from the group of proton pump inhibitors (this group of drugs is sometimes indicated by the abbreviation IPP). This substance blocks the enzyme - a proton pump (ATP-aza K + / H +) in the Pariet
al cells of the gastric mucosa, thereby inhibiting the secretion of hydrochloric acid by these cells. In this way, the acidity (pH increases) of the gastric juice decreases. The degree of inhibition depends on the dose and applies to both basal and stimulated secretion of hydrochloric acid. In addition, the gastrin secretion is increased to a degree proportional to the reduction in the acidity of the gastric juice.
Pantoprazole is rapidly absorbed after oral administration, the maximum concentration in the blood is obtained approximately 2.5 hours after administration. The meal does not affect the maximum concentration or the bioavailability of the drug, it can only delay the onset of action. After 2 weeks of treatment with pantoprazole, the symptom relief is achieved in the majority of patients. Pantoprazole is mainly metabolised in the liver with the cytochrome P450 enzyme system, most metabolites excreted in the urine, partly also in the bile. Pantoprazole passes through the placenta and into the breast milk of women.
When to use Anesteloc Max?
The preparation is indicated in adults in the short-term treatment of the symptoms of gastroesophageal reflux disease (eg heartburn, regurgitation of gastric contents).
When not to use this preparation?
Unfortunately, even if there are indications to use the preparation, it can not always be used. You can not use the product if you are allergic (you are hypersensitive) to any of the other ingredients or other benzimidazole-based medicines.
The preparation is contraindicated if atazanavir (an antiviral medicine) is used in parallel.
Contraindications during pregnancy and during breastfeeding are contraindicated.
Take special care with Anesteloc Max?
Certain diseases and other circumstances may constitute a contraindication to use or indication to change the dosage of the preparation. In some situations it may be necessary to carry out specific check-ups.
Before starting treatment, the cancerous nature of the disease should be ruled out. The use of the preparation may mask the symptoms of cancer, including stomach cancer and delay the proper diagnosis. Consult a doctor if:
· The nature of the ailment has changed or new symptoms have occurred
· Disturbing symptoms such as significant weight loss, recurrent vomiting, dysphagia, bloody vomiting, anemia, tarry stools
· You have had a stomach ulcer or you are having a gastrointestinal surgery
· Jaundice or abnormal liver function (including increased liver enzymes)
· You have other serious illnesses that affect your general well-being
· Treatment of indigestion or heartburn symptoms lasts for more than 4 weeks.
If symptoms of heartburn or indigestion persist for a long time or are recurrent, remain under medical supervision. Particularly people over 55 years old, taking a regular preparation or other medicines used to treat indigestion or heartburn, issued without a prescription, should consult a doctor.
During the period of application, other medicines from the group of proton pump inhibitors or drugs that reduce the secretion of hydrochloric acid in gastric acid from histamine type 2 (H2) receptor antagonists should not be taken in parallel.
If you expect an endoscopy or urease test, consult a physician before using the product.
The preparation does not cause immediate relief of symptoms. Usually, after about the day of use, the improvement is felt and the full relief of symptoms may require the preparation for 7 days. The preparation should not be used preventively.
The use of proton pump inhibitors may be associated with an increase in the number of naturally occurring bacteria in the upper gastrointestinal tract, as well as a slight increase in the risk of gastrointestinal infections by bacteria, such asSalmonella, Campylobacteror C. difficile.
Does this preparation affect the ability to drive vehicles?
In some people, the preparation may cause side effects such as blurred vision, dizziness and other symptoms that may impair psychophysical fitness. If these side effects occur, do not drive or operate machines or equipment.
Dosage of Anesteloc Max
The preparation is in the form of gastro-resistant tablets. It is intended for oral use. Use the preparation as recommended. Do not exceed the recommended doses because it will not increase the effectiveness of the drug and may harm your health and life. If you have any doubts regarding the use of the preparation, consult a physician.
Adults: 20 mg once daily for 2-3 days. After the symptoms have resolved, the treatment should be discontinued. Do not use it for more than 4 weeks without consulting your doctor.
If the symptoms do not improve within 2 weeks of using the preparation, a doctor should be consulted.
Do not restart the preparation without consulting your doctor.
There is no need to modify the dosage in the elderly or in patients with impaired renal or hepatic function.
Due to the lack of sufficient clinical data, it is not recommended for use in children and adolescents up to 18 years of age.
The preparation in the form of gastro-resistant tablets is intended for oral use. The tablets should be taken before a meal, swallowed whole (do not chew, chew or crumble) with water.
Can Anesteloc Max be used during pregnancy and breastfeeding?
During pregnancy, do not use any medicine without consulting your doctor!
It is very important that before using any medicine during pregnancy or breastfeeding, consult a physician and explain beyond any doubt the potential risks and benefits associated with the use of the drug.
Contraindications during pregnancy and during breastfeeding are contraindicated.
Can I use other preparations in parallel?
Tell your doctor about all medicines you have recently taken, including those that are over the counter.
Pantoprazole reduces the secretion of hydrochloric acid in the stomach and thus reduces the acidity (increases the pH) of gastric juice. Therefore, pantoprazole may reduce the absorption of certain drugs, such as, for example, antifungal azole (ketoconazole, Itraconazole
, posaconazole), erlotinib.
It must not be used with atazanavir.
In parallel use of the preparation with anticoagulants, coumarin derivatives (warfarin, phenprocoumon), prothrombin time and INR are recommended at the beginning of treatment, after completion and if irregular use of pantoprazole.
Pantoprazole is metabolised in the liver with the cytochrome P450 enzyme system. To date, there has been no clinically significant interaction of pantoprazole with drugs that are metabolised by cytochrome P450.
There was no interaction of pantoprazole with antacids or with antibiotics such as Clarithromycin
What side effects can occur?
Like all medicines, Anesteloc Max may cause side effects, although they will not occur in all patients who use this medicine. Remember that the expected benefits of using the drug are usually greater than the damage resulting from the occurrence of side effects.
Uncommon: sleep disturbances, headache and dizziness, nausea, diarrhea, vomiting, constipation, flatulence, abdominal fullness, dry mouth, epigastric pain and discomfort, increased liver enzymes, weakness, fatigue, malaise, allergic reactions (pruritus, rash, eczema, eruptions). Rarely or very rarely: hematological disorders (leukopenia, thrombocytopenia), hypersensitivity and Anaphylactic reactions
(including urticaria, angioneurotic edema
, eg on the face, larynx, tongue, throat that may impede breathing, anaphylactic shock), increased lipid levels (triglycerides, cholesterol) , weight changes, depression, confusion, blurred vision, increased bilirubin, joint pain, myalgia, gynecomastia, increased body temperature, peripheral edema. In addition, hyponatraemia, hypomagnesaemia, hallucinations, confusion, liver cell damage leading to jaundice, sometimes with hepatic failure, interstitial nephritis, community acquired pneumonia, osteoporosis and hip fracture, carpal or spinal bones, hypersensitivity to light, may occur with an unknown frequency. severe skin reactions, including Stevens and Johnson syndrome, toxic epidermal necrolysis, erythema multiforme.
Other preparations on the Polish market containing pantoprazole
Anesteloc (enteric-coated tablets)
Contix (enteric-coated tablets)
Contix ZRD (enteric-coated tablets)
Contracid (enteric-coated tablets)
Controloc (powder for solution for injection)
Controloc 20 (enteric-coated tablets)
Controloc 40 (enteric-coated tablets)
Controloc Control (enteric-coated tablets)
Gastrostad (enteric-coated tablets)
Gerdin (enteric-coated tablets)
Gerdin Max (gastro-resistant tablets)
IPP (powder for solution for injection)
IPP 20 (enteric-coated tablets)
IPP 40 (enteric-coated tablets)
Noacid (enteric-coated tablets)
Nolpaza 20 mg (enteric-coated tablets)
Nolpaza 40 mg (enteric-coated tablets)
Nolpaza Control (coated tablets)
Ozzion (enteric-coated tablets)
Pamyl 20 mg (enteric-coated tablets)
Pamyl 40 mg (enteric-coated tablets)
Panprazox (enteric-coated tablets)
Panrazol (enteric-coated tablets)
Pantogen 40 mg (enteric-coated tablets)
Pantopraz 20 mg (enteric-coated tablets)
Pantopraz 40 mg (enteric-coated tablets)
Pantopraz Bio (enteric-coated tablets)
Pantoprazole Krka (enteric-coated tablets)
Pantoprazole Teva (enteric-coated tablets)
Pantamrazole Vitama (enteric-coated tablets)
Pantoprazole Bluefish (enteric-coated tablets)
Pantoprazole Genoptim (enteric-coated tablets)
Pantoprazole Genoptim SPH (enteric-coated tablets)
Pantoprazole Mercapharm (enteric-coated tablets)
Panzol (enteric-coated tablets)
Panzol Pro (enteric-coated tablets)
Prazopant (powder for solution for injection)
Ranloc (enteric-coated tablets)
Ranloc Med (enteric-coated tablets)
Xotepic (enteric-coated tablets)