► ACC (acetylcysteine) - Practical Medicine

ACC (acetylcysteine) - tablets

The name of the preparation Character; dose; package Manufacturer Price 100% Price after refund In which pharmacy?
ACC tablets; 200 mg; 20 tables Sandoz 14.18 Check

Note: reimbursed drug prices are in line with the regulations in force from July 1, 2018.

The preparation contains the substance:acetylcysteine

The drug is available without a prescription

What is ACC?

Mucolytic drug, thins secretions in the airways and facilitates its removal.

What does ACC contain and how does it work?

The active substance is Acetylcysteine . It is a derivative of the cysteine ​​amino acid. Acetylcysteine ​​increases the secretion of mucus in the airways, reduces its viscosity and liquefies obstructing secretions and facilitates its transport (improves the function of the respiratory epithelium). In this way, it helps to clear the airways, facilitates expectoration, does not disturb the natural cough reflex. Acetylcysteine ​​is also used as an antidote for Paracetamol poisoning.

When to use ACC?

The preparation is indicated as a drug that dilutes the airway secretion and facilitates its expectoration in patients with bronchitis associated with colds.

When not to use this preparation?

Unfortunately, even if there are indications to use the preparation, it can not always be used. You can not use the preparation if you are allergic (you are hypersensitive) to any of the ingredients. You can not use the preparation if you are present:
· Active peptic ulcer of the stomach or duodenum
· Acute asthmatic condition
· Reduced expectoration ability of secretions.
Do not use in children under 6 years of age.
Do not use in pregnant women or women during breastfeeding, due to the lack of sufficient data on safety and efficacy.

When should you take special care with ACC?

Certain diseases and other circumstances may constitute a contraindication to use or indication to change the dosage of the preparation. In some situations it may be necessary to carry out specific check-ups. Therefore, before using the preparation, you should consult a doctor if you have ever been diagnosed with peptic ulcer disease, respiratory failure or if you have asthma. In the above cases, and if you are an elderly person (after the age of 65), caution should be exercised. Patients with asthma are at risk of developing bronchospasm.
The use of the preparation may cause liquefaction and increase the volume of bronchial secretions. If the patient has a reduced coughing ability and is unable to expectorate effectively, appropriate medical treatment, such as drainage and suctioning, is necessary.
The use of acetylcysteine ​​in children up to 2 years of age may cause airflow obstruction and obstruction. Mucolytics should not be used in this age group.
If it is necessary to take oral antibiotics in parallel, a minimum of two hours should be allowed between taking them and taking the medicine.
Very rarely, the use of the preparation may be associated with severe skin reactions such as Stevens and Johnson syndrome and toxic epidermal necrolysis. If new lesions appear on the skin or mucous membranes, stop using the product immediately and consult a physician.
The preparation is intended for short-term use.
Caution should be exercised in people with histamine intolerance, because acetylcysteine ​​affects the metabolism of histamine and may cause symptoms of intolerance, such as headache, rhinitis or pruritus.
Additional information about the other ingredients of the preparation:
· The preparation in the form of tablets and effervescent tablets contains lactose; people with galactose intolerance, lactase deficiency or malabsorption of Glucose -galactose, should not use this preparation
· The effervescent tablet preparation contains sodium (1 effervescent tablet contains 98.8 mg of sodium), which should be taken into account in the case of renal dysfunctions and patients using a diet with low sodium content (including the salt-free diet)
· The powder formulation for the preparation of the oral solution contains sucrose; people with inherited disorders associated with fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase deficiency should not use the preparation.

Does this preparation affect the ability to drive vehicles?
There are no data on the effect of the preparation on the ability to drive and use machines / machines.

Dosage of ACC preparation

The preparation is in the form of tablets, effervescent tablets or powder for the preparation of an oral solution. Do not exceed the recommended doses because it will not increase the effectiveness of the drug and may harm your health and life. If you have any doubts regarding the use of the preparation, consult a physician.
Adults and adolescents after 14 years of age: 200 mg 2-3 times daily.
Children 6-14. year of life: 200 mg twice daily; if it is necessary to give a daily dose of 300 mg, use the ACC Mini.
The preparation should be taken after a meal. The method of taking depending on the form of the preparation:
· The tablet can be swallowed (without chewing) with a sufficient amount of liquid or dissolved in 0.5 glasses of water and drink immediately after reconstitution; prepared to drink the solution should not have a long contact with metals or with rubber;
· The effervescing tablet should be dissolved in 0.5 glasses of water and drunk immediately after reconstitution; prepared to drink the solution should not have a long contact with metals or with rubber;
· Powder for the preparation of an oral solution: the contents of the sachet should be dissolved in a cool liquid (eg water, juice, tea) and drunk immediately after reconstitution; prepared to drink the solution should not have a long contact with metals or with rubber.
It is beneficial to take an increased amount of fluids during the treatment period. The preparation should not be used immediately before bedtime (no later than 4 hours before bedtime).
It should not be used for more than 4-5 days without the doctor's recommendation.
It should not be used in children under 6 years of age.

Can I use ACC during pregnancy and breastfeeding?

During pregnancy, do not use any medicine without consulting your doctor!
It is very important that before using any preparation during pregnancy or breastfeeding, consult a physician and explain beyond any doubt the potential risks and benefits associated with the use of the drug. If you are pregnant or plan to become pregnant before using the preparation, consult a doctor.
There are insufficient data on the safety and efficacy of the preparation in pregnant women and in breast-feeding women and should not be used in these groups of women.

Can I use other preparations in parallel?

Tell your doctor about all medicines you have recently taken, including those that are over the counter.
You should not take medicines that inhibit the cough reflex (anti-tussive medicines, such as codeine), because this reflex promotes the removal of large secretion after liquefaction. The parallel use of antitussives and the preparation may cause dangerous secretion of the secretion due to the reduction of the cough reflex.
When using acetylcysteine ​​and oral antibiotics, at least a 2-hour interval should be maintained between taking these drugs due to the risk of inactivation of antibiotics.
The combined use of acetylcysteine ​​and Nitroglycerin e or other nitrates may lead to increased vasodilation and inhibition of platelet aggregation. Be careful.

What side effects can occur?

Like all medicines, ACC can also cause side effects, although they will not occur in all patients who use this medicine. Remember that the expected benefits of using the drug are usually greater than the damage resulting from the occurrence of side effects.
Uncommon: headaches, tinnitus, increased heart rate (tachycardia), hypotension, oral mucositis, nausea, diarrhea, vomiting, abdominal pain, fever, hypersensitivity reactions (pruritus, urticaria, rash, angioneurotic edema ) ). Rare: dyspepsia , dyspnea, bronchospasm. Very rare: haemorrhage, Anaphylactic reactions , including life-threatening anaphylactic shock. Possible severe skin reactions, including Stevens and Johnson syndrome, and toxic epidermal necrolysis. Acetylcysteine ​​reduces platelet aggregation (the clinical significance of this phenomenon is unknown).

Other preparations on the Polish market containing acetylcysteine

ACC (effervescent tablets)
ACC classic (oral solution)
ACC Hot (for oral solution)
ACC mini (effervescent tablets)
ACC mini (powder for oral solution)
ACC optima (effervescent tablets)
ACC optima Active (powder)
ACC optima Hot (powder for oral solution)
Acetylcysteine ​​Sandoz (solution for infusion)
Fluimucil Forte (effervescent tablets)
Fluimucil Muko (for oral solution)
Fluimucil Muko Junior (for oral solution)
Muccosinal (effervescent tablets)
Nacecis (effervescent tablets)
Tussicom 200 (powder for solution)
Tussicom 400 (powder for solution)
Tussicom 600 (powder for solution)