|The name of the preparation||Character; dose; package||Manufacturer||Price 100%||Price after refund||In which pharmacy?|
|Atrovent N||inhalation aerosol, solution; 20 μg / inhalation dose; 200 doses [10 ml]||Boehringer Ingelheim International||19.34||
Note: reimbursed drug prices are in line with the regulations in force from July 1, 2018.
An inhalation drug that prevents spastic bronchial and bronchodilatory states facilitating the free flow of air in the airways. The drug is used in diseases with bronchospasm. The effect occurs after a few minutes and lasts an average of up to 6 hours.
The active substance is ipratropium bromide. It is a substance belonging to a group of medicines called parasympatolytics or cholinolytics. It works anti-spastically, it dilates the bronchi and prevents their cramps. The mechanism of action of ipratropium is to inhibit the activation of cholinergic receptors (specifically muscarinic receptors type M3) of the smooth muscle cells of the bronchi located in the membrane. These receptors are stimulated by acetylcholine released after activation of the vagus nerve and cause contraction of the bronchial smooth muscles. Inhibition of their activation leads to bronchodilation. Improves the ventilation of the lungs, and the patient feels the reduction or complete resolution of dyspnea caused by the contraction of the muscles of the respiratory tract.
The preparation is indicated as a bronchodilator in the maintenance treatment of bronchospasm:
• in chronic obstructive pulmonary disease (COPD)
• in bronchial asthma.
Unfortunately, even if there are indications to use the preparation, it can not always be used. You must not use the product if you are allergic (you are hypersensitive) to any of the ingredients or to atropine and atropine like substances.
Certain diseases and other circumstances may constitute a contraindication to use or indication to change the dosage of the preparation. In some situations it may be necessary to carry out specific check-ups. Therefore, before using the preparation you should consult a doctor if you suspect or have been diagnosed with:
• prostatic hyperplasia
• narrowing of the bladder neck
• predisposition to glaucoma with a closing angle of perception.
Cystic fibrosis patients may be more susceptible to gastrointestinal motility disorders.
Protect eyes from contact with the preparation. The aerosol should be used according to the instructions below. People with a predisposition to glaucoma should take special care and very carefully protect their eyes during inhalation. The preparation after entering the eye may cause dilation of the pupils, increase in intraocular pressure, glaucoma with a closed angle of perception, eye pain.If symptoms such as eye pain, discomfort, blurred vision, visual halo, altered vision of colors coexisting with eye redness occur, immediately consult a physician. These symptoms may indicate an acute glaucoma with a closed angle of perception, and it may be necessary to use appropriate medications.
Rarely, the preparation may cause immediate hypersensitivity reactions such as urticaria, angioneurotic edema , rash, bronchospasm, swelling of the mucous membrane of the mouth and throat, and anaphylactic shock.
If the existing shortness of breath is a violent attack and its symptoms are rapidly increasing, you should seek medical help immediately. If the treatment does not bring significant improvement or the symptoms become worse, please consult your doctor. Your doctor will assess your condition and verify your further treatment.
For fresh exacerbations of chronic obstructive pulmonary disease (COPD), consult a physician.
Additional information about the other ingredients of the preparation:
- the preparation does not contain CFC (chlorofluorocarbon), which may cause a slight difference in taste in relation to previously used aerosols; this difference does not affect the effectiveness and safety of the preparation in any way; the product contains HFA 134a (tetrafluoroethane);
- the preparation contains anhydrous ethanol (8.415 mg / dose).
Important information about the use of the preparation.
The delivered dose depends on properly conducted inhalation. That is why it is very important to master the inhalation technique corr ectly. Inhalation of the drug allows its rapid access directly to the airways, that is to the place of its operation. After using the number of doses declared by the manufacturer, a certain amount of the preparation may remain in the container, but further use does not ensure the delivery of the correct dose. The container should be replaced with a new one.
• To always buy your prescription in time and buy a new one before you use up the previous one.
• Always have your inhaler with you.
• The mouthpiece is intended for use only with the preparation for which it has been specially designed. Never use this mouthpiece in other containers.
- Keep the inhaler clean. The mouthpiece should be washed with warm water with the addition of soap or detergent, then rinsed.
Does this preparation affect the ability to drive vehicles?
There are no studies on the effect of the preparation on the ability to drive and use machines.
Use the product as directed by your doctor. The preparation is intended for inhalation use only. Do not exceed the recommended doses, because it will not increase the effectiveness of the drug and may harm your health and life. If you have any doubts regarding the use of the preparation, consult a physician. The doctor adjusts the dosage to the individual needs of the patient. Unless otherwise directed by your doctor, the following doses are usually used.
Adults and children after the age of 6:
2 doses (spray) 4 times a day
The need to increase doses may indicate the need for additional drugs; consult a physician who will verify the treatment and, if necessary, recommend changing the dosage or adding other preparations.
Do not exceed the maximum dose, which is 12 sprays per day.
Due to limited information on the use of the product in children, it should only be used at the express request of a doctor and under the supervision of an adult.
During pregnancy, do not use any medicine without consulting your doctor!
It is very important that before using any medicine during pregnancy or breastfeeding, consult a physician and explain beyond any doubt the potential risks and benefits associated with the use of the drug. If you are pregnant or plan to become pregnant, please inform the doctor prescribing the prescription for this medicine.
The safety of the preparation during pregnancy has not been established. Only a doctor can assess the risk-benefit ratio in your case.
It is not known if the product is excreted in human milk. Before using the product during breastfeeding, consult a doctor.
Tell your doctor about all medicines you have recently taken, including those that are over the counter.Interactions of ipratropium bromide and drugs acting on beta-adrenergic receptors (eg sympathomimetics such as fenoterol, formoterol, salmeterol) and xanthine-derived drugs (eg theophylline) may enhance the bronchodilator effect.
Like all medicines, Atrovent N can cause side effects, although they will not occur in all patients who use this medicine. Remember that the expected benefits of using the drug are usually greater than the damage resulting from the occurrence of side effects.
After the use of the preparation may occur: headache and dizziness, disturbances of eye accommodation, glaucoma with a closed angle of perception, acceleration of heart function, constipation, diarrhea, vomiting, skin hypersensitivity reactions (rash, pruritus, urticaria, Quincke's edema). The rare but serious side effects include: anaphylactic type hypersensitivity reactions (angioneurotic edema of the lips, tongue, throat that may impede breathing and / or swallowing, shortness of breath, bronchospasm, hypotension, shock). If you notice any signs of anaphylactic reaction, you should seek medical help immediately. This preparation, like other inhalation medicines, may cause respiratory irritation, cough, dry mouth, and (rarely) bronchospasm. After getting into the eye, the preparation may cause dilation of the pupils, increase in intraocular pressure, glaucoma with a closing angle of perception, and eye pain. If symptoms such as eye pain, discomfort, blurred vision, visual halo, changes in color vision coexisting with red eyes occur, immediately consult a physician. These symptoms may be signs of glaucoma with a closed angle of perception, which may require appropriate treatment. Urinary retention may rarely occur (especially in people with pre-existing urinary outflow obstruction), and, especially when high doses are used, cardiac arrhythmias may occur, including atrial fibrillation, sUPRA ventricular tachycardia and accessory spasms.