Note: reimbursed drug prices are in line with the regulations in force from July 1, 2018.
A preparation containing Magnesium
in the form of hydrogen pyroginate.
Magnesium takes part in numerous metabolic changes in the body, such as the synthesis and use of high-energy compounds and the synthesis of many enzymes.
It exerts a stabilizing effect on cell membranes. Maintains the state of mitochondria - so-called energy centers of the cell. Magnesium protects the lysosomes, it is needed to maintain the stability of the ribosomes and allows binding of mRNA to ribosomes. It is therefore the main cellular and intracellular stabilizer and participates in all basic physiological activities.
Magnesium has neurotropic activity, which causes its calming effect, and deficiency - neuromuscular hyperactivity. It exerts a depressive effect on the autonomic nervous system, and in excess it can lead to the paralysis of nerve ganglia. It also reduces the excitability of striated muscle fibers.
Magnesium has a protective effect on the heart muscle, reducing its hypoxia. Extends the time of conduction of stimuli in the infra-conducting system. It counteracts the accumulation of Calcium
and connective tissue changes in the vascular walls. It is also a physiological antithrombotic factor that stabilizes platelets. It improves phagocytosis and lymphocyte production, which leads to alleviation of the inflammatory process.
Magnesium is involved in the development and mineralization of bones, and its deficiency causes faster aging of bone tissue. It is also necessary for the synthesis of certain hormones, e.g. insulin
Magnesium participates in numerous defense processes of the system. It counteracts stress, hypoxia, allergy and inflammation, and stimulates phagocytosis and activates the complement system.
In cases of magnesium deficiency, neuromuscular hypersensitivity is observed, which may be manifested by tetany attacks. There are muscular tremors, generalized tonic-clonic contractions and athetic movements. Apathy, weakness, dizziness, mental disorders like neurosis, anxiety and confusion are also observed. Non-regularity of the heart may occur, increased susceptibility to stress and reduced resistance to infection.
Magnesium deficiency may be the result of its insufficient content in foods. It is also found in chronic alcoholism or in non-magnesium containing liquids during long-term parenteral nutrition. The disturbances of magnesium absorption occur in the syndrome of poor digestion and absorption as well as in liver cirrhosis. Also, excessive loss of magnesium by the kidneys leads to a deficiency.
Magnesium deficiency is accompanied by diseases such as chronic nephritis, polyuria phase in patients with acute renal failure
, overactive thyroid and parathyroid glands, primary and secondary hyperaldosteronism syndrome, multiple myeloma and metastasis to the bone, and overdose of vitamin D.
The high magnesium loss can occur through the digestive tract in chronic vomiting.
Asmag B contains additionally Pyridoxine
, which allows the active transport of magnesium and extends its residence time in the body. It also increases magnesium concentrations in erythrocytes and reduces its excretion in the urine.
The preparation is indicated for use in cases of magnesium deficiency in the body.
Unfortunately, even if there are indications to use the preparation, it can not always be used. You can not use the preparation if you are allergic (you are hypersensitive) to any of the ingredients.
Contraindications to the use of the preparation are also:
severe renal failure (creatinine clearance below 30 ml / minute)
atrioventricular conduction disorders (block)
Certain diseases and other circumstances may constitute a contraindication to use or indication to change the dosage of the preparation. In some situations it may be necessary to carry out specific check-ups.
Taking the product at a higher dose than recommended may have a laxative effect
Information on additional components of the preparation:
The preparation contains lactose; people with inherited disorders associated with galactose intolerance, lactase deficiency or Glucose
-galactose malabsorption should not use it.
Impact on the machine operation capability:
The preparation used in accordance with the recommendations does not affect the ability to drive motor vehicles, use machines and psychophysical fitness.
The preparation is in the form of tablets for oral use. Use the preparation as recommended. Do not exceed the recommended doses because it will not increase the effectiveness of the drug and may harm your health and life. If you have any doubts regarding the use of the preparation, consult a physician.
Asmag, Asmag B:
Adults: 3 tablets 4 times a day.
Children: 1 tablet 2 or 3 times a day.
Adults: 1 or 2 tablets 3 times a day.
The preparation should be used orally after a meal.
Tell your doctor about all medicines you have recently taken, including those that are over the counter.
The use of the preparation in parallel with Tetracycline
antibiotics, oral anticoagulants (derivatives of hydroxycoumarin), preparations containing phosphates or calcium and iron compounds leads to mutual reduction of absorption from the gastrointestinal tract. At least a 2-hour interval should be maintained between taking these preparations.
Like all medicines, Asmag and Asmag forte can cause side effects, although they will not occur in all patients who use this medicine. Remember that the expected benefits of using the drug are usually greater than the damage resulting from the occurrence of side effects.
A preparation administered in a dose greater than the recommended dose may cause diarrhea, nausea, vomiting.